What are the signs and symptoms of Hunter syndrome?

Hunter syndrome has a variety of signs and symptoms. Hunter syndrome can affect any part of the body. The symptoms of Hunter syndrome, and their progress and severity, are different in each person.

It is important to remember that many of these signs and symptoms are common in childhood, and it is the combination of them that may indicate Hunter syndrome. Not all patients will have all of the signs and symptoms, and they progress differently, so there is no typical patient experience.

There are two types of Hunter syndrome; these are known as neuronopathic (with cognitive impairment) and non-neuronopathic (without cognitive impairment). Both types experience signs and symptoms that affect the body, but the neuronopathic type also has symptoms that affect the brain and nervous system, meaning that behaviour and development are also affected. Nearly 7 out of 10 people with Hunter syndrome have the neuronopathic type of the disease.

Symptoms usually show between the ages of 2 and 4 years in the neuronopathic type, whereas the non-neuronopathic type generally presents symptoms later in childhood.

Learn more about how these families are living with Hunter syndrome